Adult Men and Women Who Suffer From Chronic Depression

Market surveys on women, men and depression suggest an estimated 4.4 million Americans are believed to suffer from chronic treatment-resistant depression. Depression is a chronic, disabling disorder and a major worldwide public health problem. Depressive episodes usually recur over time, with risk for further episodes proportional to the number of prior episodes. After three major depressive episodes, the probability of recurrence is 90%. In the U.S. alone, approximately 18 million people suffer from depression over six million of which are receiving some form of medical treatment.

Market studies on women, men and depression also estimate that over 100,000 Americans each year are treated with electro convulsive therapy (ECT) for their depression. Roughly 15% of all people with severe depression that require hospitalization commit suicide. Disorders related to men and depression are also very expensive. Depression is ranked as the second leading cause of disability worldwide in 1990. Depression costs in the U.S. alone are estimated to exceed $50 billion annually, including over $12 billion in direct treatment costs. The total market in the U.S. for anti-depressants is estimated to exceed $6 billion.

Several general factors may be linked to women, men and depression but the exact causes of depressive disorders are unknown, although both biological abnormalities and psychological factors are thought to precipitate this disease. Diminished synaptic concentrations of neurotransmitters, especially serotonin and norepinephrine, are implicated in the pathogenesis of depression. Most current standard therapies regarding men and depression are thought to affect either one or both of these neurotransmitter systems (1) SSRI drugs (serotonin-specific reuptake inhibitors) or (2) MAOI drugs (monoamine oxidase inhibitors) that decrease the breakdown of norepinephrine and serotonin. It is of interest to note that several antiepileptic compounds, such as carbamazepine, valproate and lamotrigine, are used as mood stabilizers and that lamotrigine and gabapentin are also used as antidepressants.

There is a new alternative treatment for this debilitating disease. On June 15th, 2004 an FDA Medical Device Advisory Panel recommended approval of the vagus nerve stimulator as a treatment for chronic or treatment-resistant depression. Learn more about this remarkable device at www.VagusNerveStimulator.com.

Charles E. Donovan, III
Author
Out of the Black Hole: The Patient's Guide to Vagus Nerve Stimulation and Depression. Published November 1, 2004 by Wellness Publishers,L.L.C.

MORE RESOURCES:

World heading for Great Depression II - Inquirer.net

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Stephen King: Lessons from the Great Depression of the 1930s have ... - Independent

table border=0 width= valign=top cellpadding=2 cellspacing=7trtd valign=top class=jfont style=font-size:85%;font-family:arial,sans-serifbrdiv style=padding-top:0.8em;img alt= height=1 width=1/divdiv class=lha href=http://news.google.com/news/url?sa=Tct=us/1-0fd=Rurl=http://www.independent.co.uk/news/business/comment/stephen-king/stephen-king-lessons-from-the-great-depression-of-the-1930s-have-not-been-learnt-959408.htmlcid=1256387476ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNE5xNjpTEQycJHCORVHfsaHud2e5AStephen King: Lessons from the Great bDepression/b of the 1930s have b.../b/abrfont size=-1font color=#6f6f6fIndependent,nbsp;UKnbsp;-/font nobr58 minutes ago/nobr/fontbrfont size=-1Already, this ranks as the fifth biggest stock market decline since the 1920s, beaten only by the 1929 Wall Street Crash (and the ensuing bDepression/b in the b.../b/fontbrfont size=-1a href=http://news.google.com/news/url?sa=Tct=us/1-1fd=Rurl=http://www.nytimes.com/2008/10/13/business/13views.html%3Fref%3Dbusinesscid=1256387476ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNFA-ENSnDgdJtMlkZYSK0yKyTB7DABreakingviews.com Crisis Is Milder Outside Finance/a font size=-1 color=#6f6f6fnobrNew York Times/nobr/font/fontbrfont size=-1a href=http://news.google.com/news/url?sa=Tct=us/1-2fd=Rurl=http://seattletimes.nwsource.com/html/jontalton/2008256738_biztaltoncol12.htmlcid=1256387476ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNGg6uoBjIvhkSdO38gxyGfVIK5gXwOn the Economy The Great Disruption hits Puget Sound hard/a font size=-1 color=#6f6f6fnobrSeattle Times/nobr/font/fontbrfont class=p size=-1a class=p href=http://news.google.com/news?sourceid=navclientie=ISO-8859-1rls=GGLG,GGLG:2005-22,GGLG:enncl=1256387476hl=ennobrall 3 news articles/nobr/a/font/div/font/td/tr/table

Fed chief guided by lessons from Depression - San Francisco Chronicle

table border=0 width= valign=top cellpadding=2 cellspacing=7trtd width=80 align=center valign=topfont style=font-size:85%;font-family:arial,sans-serifa href=http://news.google.com/news/url?sa=Tct=us/2i-0fd=Rurl=http://www.chinadaily.com.cn/world/2008-10/08/content_7087415.htmcid=1255009308ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNFEIlAtS8oIFfryz-Z0p4eTpt4xbwimg src=http://news.google.com/news?imgefp=Olnj7YBBckkJimgurl=www.chinadaily.com.cn/world/images/attachement/jpg/site1/20081008/0013729e47710a566e7435.jpg width=80 height=59 alt= border=1brfont size=-2China Daily/font/a/font/tdtd valign=top class=jfont style=font-size:85%;font-family:arial,sans-serifbrdiv style=padding-top:0.8em;img alt= height=1 width=1/divdiv class=lha href=http://news.google.com/news/url?sa=Tct=us/2-0fd=Rurl=http://www.sfgate.com/cgi-bin/article.cgi%3Ffile%3D/c/a/2008/10/12/MNJ013F0VO.DTLcid=1255009308ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNGlNiD9q2N0DmC2BSB1gfKSxi6KagFed chief guided by lessons from bDepression/b/abrfont size=-1font color=#6f6f6fSan Francisco Chronicle,nbsp; USAnbsp;-/font nobr16 hours ago/nobr/fontbrfont size=-1The chairman of the Federal Reserve is also one of the nation#39;s pre-eminent scholars of the Great bDepression/b. As the world careens through a global b.../b/fontbrfont size=-1a href=http://news.google.com/news/url?sa=Tct=us/2-1fd=Rurl=http://www.youtube.com/watch%3Fv%3DFa_Zw2Ty_Xocid=1255009308ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNHA0Hvxc2MruXlhxbwtt_6QJyfI2wVideo: Bernanke: More Economic Pain Ahead/a font size=-1 color=#6f6f6fnobrAssociatedPress/nobr/fontobject width=448 height=356param name=movie value=http://www.youtube.com/v/Fa_Zw2Ty_Xo/paramparam name=wmode value=transparent/paramembed src=http://www.youtube.com/v/Fa_Zw2Ty_Xotype=application/x-shockwave-flashwmode=transparentwidth=448height=356/embed/objectbr/fontfont size=-1a href=http://news.google.com/news/url?sa=Tct=us/2-2fd=Rurl=http://ap.google.com/article/ALeqM5j9bxucmQP6KIcNs3d7g7zxe0mcLAD93LT6LG1cid=1255009308ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNENTTP9A1sn_GrubLmPEdvP4l_ZagFed assumes powerful new role in financial crisis/a font size=-1 color=#6f6f6fnobrThe Associated Press/nobr/font/fontbrfont size=-1a href=http://news.google.com/news/url?sa=Tct=us/2-3fd=Rurl=http://economix.blogs.nytimes.com/2008/10/08/in-praise-of-bernanke/cid=1255009308ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNECeCmr9iyonARtrDDIJt2_IegBHAIn Praise of Bernanke/a font size=-1 color=#6f6f6fnobrNew York Times/nobr/font/fontbrfont size=-1 class=pa href=http://news.google.com/news/url?sa=Tct=us/2-4fd=Rurl=http://www.reuters.com/article/reutersEdge/idUSTRE4968I020081007cid=1255009308ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNFSxQQvf-efTLWn9P_dV7tdT405ZgnobrReuters/nobr/anbsp;- a href=http://news.google.com/news/url?sa=Tct=us/2-5fd=Rurl=http://seekingalpha.com/article/98975-fed-watch-just-the-timing-is-in-doubtcid=1255009308ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNHWOkAqmRWw89fCOu60QA1_e_-kHQnobrSeeking Alpha/nobr/a/fontbr/font class=p size=-1a class=p href=http://news.google.com/news?sourceid=navclientie=ISO-8859-1rls=GGLG,GGLG:2005-22,GGLG:enncl=1255009308hl=ennobrall 1,688 news articles/nobr/a/font/div/font/td/tr/table

Norbert weakens to tropical depression over Mexico - The Associated Press

table border=0 width= valign=top cellpadding=2 cellspacing=7trtd width=80 align=center valign=topfont style=font-size:85%;font-family:arial,sans-serifa href=http://news.google.com/news/url?sa=Tct=us/3i-0fd=Rurl=http://news.bbc.co.uk/2/hi/americas/7665021.stmcid=1254838176ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNHZqX7sa4e8bSu2s7nQcdx7qDRtrgimg src=http://news.google.com/news?imgefp=VqeGMp8jNugJimgurl=newsimg.bbc.co.uk/media/images/45099000/jpg/_45099385_-50.jpg width=80 height=60 alt= border=1brfont size=-2BBC News/font/a/font/tdtd valign=top class=jfont style=font-size:85%;font-family:arial,sans-serifbrdiv style=padding-top:0.8em;img alt= height=1 width=1/divdiv class=lha href=http://news.google.com/news/url?sa=Tct=us/3-0fd=Rurl=http://ap.google.com/article/ALeqM5gEhzSsWOgWU_7qqk0Pi86kLVtWiwD93P18080cid=1254838176ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNGK4FuF-HinYzLute96KLz-IwuI7wNorbert weakens to tropical bdepression/b over Mexico/abrfont size=-1font color=#6f6f6fThe Associated Pressnbsp;-/font nobr10 hours ago/nobr/fontbrfont size=-1PUERTO SAN CARLOS, Mexico (AP) — Norbert dissipated into a tropical bdepression/b over the northern mountains of mainland Mexico on Sunday, after ripping off b.../b/fontbrfont size=-1a href=http://news.google.com/news/url?sa=Tct=us/3-1fd=Rurl=http://www.youtube.com/watch%3Fv%3DI03cuEqZE_Ycid=1254838176ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNGogx3mTPdAWVu_1cdXNBpTkiCzagVideo: Mexico Mops Up After Marco, Eyes Norbert/a font size=-1 color=#6f6f6fnobrAssociatedPress/nobr/fontobject width=448 height=356param name=movie value=http://www.youtube.com/v/I03cuEqZE_Y/paramparam name=wmode value=transparent/paramembed src=http://www.youtube.com/v/I03cuEqZE_Ytype=application/x-shockwave-flashwmode=transparentwidth=448height=356/embed/objectbr/fontfont size=-1a href=http://news.google.com/news/url?sa=Tct=us/3-2fd=Rurl=http://in.reuters.com/article/worldNews/idINIndia-35821720081006cid=1254838176ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNHGcPE_bO1gle6uMzLGV00TYPyhewbDepression/b may form in Mexico#39;s Bay of Campeche - NHC/a font size=-1 color=#6f6f6fnobrReuters India/nobr/font/fontbrfont size=-1a href=http://news.google.com/news/url?sa=Tct=us/3-3fd=Rurl=http://www.bymnews.com/news/newsDetails.php%3Fid%3D43799cid=1254838176ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNEJR725nKISnfNwGvrQMWj5C1IWyQHurricane Hunter aircraft to investigate tropical bdepression/b in b.../b/a font size=-1 color=#6f6f6fnobrBYM News (press release)/nobr/font/fontbrfont size=-1 class=pa href=http://news.google.com/news/url?sa=Tct=us/3-4fd=Rurl=http://www.cfnews13.com/Weather/HurricaneCenter/2008/10/6/tropical_depression_13_swirls_near_mexico.htmlcid=1254838176ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNHsJeSidxs5ZO4sfdTfdbDazzRlpAnobrCentral Florida News 13|/nobr/anbsp;- a href=http://news.google.com/news/url?sa=Tct=us/3-5fd=Rurl=http://www.alertnet.org/thenews/newsdesk/N06389352.htmcid=1254838176ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNHF2ErvCs-L92QEhL61bZ371OiuognobrReuters AlertNet/nobr/a/fontbr/font class=p size=-1a class=p href=http://news.google.com/news?sourceid=navclientie=ISO-8859-1rls=GGLG,GGLG:2005-22,GGLG:enncl=1254838176hl=ennobrall 5,379 news articles/nobr/a/font/div/font/td/tr/table

Could America be heading for another Depression? - KHOU

Scotland 0 Norway 0: Scotland slump into depression - Independent

Prostitution Still a Safe Bet in New Depression - Gawker

table border=0 width= valign=top cellpadding=2 cellspacing=7trtd width=80 align=center valign=topfont style=font-size:85%;font-family:arial,sans-serifa href=http://news.google.com/news/url?sa=Tct=us/6i-0fd=Rurl=http://gawker.com/5062375/prostitution-still-a-safe-bet-in-new-depressioncid=1256928037ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNFAlWq8tjryDI0uIA7Sh3nEm0LPYAimg src=http://news.google.com/news?imgefp=3UqEeMgFSBQJimgurl=cache.gawker.com/assets/images/2008/10/custom_1223833583981_jamieleecurtisnudecelebs677.jpg width=80 height=67 alt= border=1brfont size=-2Gawker/font/a/font/tdtd valign=top class=jfont style=font-size:85%;font-family:arial,sans-serifbrdiv style=padding-top:0.8em;img alt= height=1 width=1/divdiv class=lha href=http://news.google.com/news/url?sa=Tct=us/6-0fd=Rurl=http://gawker.com/5062375/prostitution-still-a-safe-bet-in-new-depressioncid=1256928037ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNFAlWq8tjryDI0uIA7Sh3nEm0LPYAProstitution Still a Safe Bet in New bDepression/b/abrfont size=-1font color=#6f6f6fGawker,nbsp;NYnbsp;-/font nobr7 hours ago/nobr/fontbrfont size=-1Like the drug trade, booze, and motion pictures, prostitution can muster through any economy. Although New York City#39;s ladies of the evening say that the b.../b/font/div/font/td/tr/table

Beneath the financial crisis waits a nastier beast - Sydney Morning Herald

Geniuses Mike Huckabee and Chuck Norris Compare Depression ... - Gawker

table border=0 width= valign=top cellpadding=2 cellspacing=7trtd width=80 align=center valign=topfont style=font-size:85%;font-family:arial,sans-serifa href=http://news.google.com/news/url?sa=Tct=us/8i-0fd=Rurl=http://gawker.com/5062332/geniuses-mike-huckabee-and-chuck-norris-compare-depression-conspiraciescid=1256896686ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNFFSrld8gfrlM0IDsN72e21HZ5xLgimg src=http://news.google.com/news?imgefp=4vA5KuPfD6oJimgurl=cache.gawker.com/assets/images/2008/10/custom_1223825258430_s-CHUCK-HUCK-large.jpg width=80 height=58 alt= border=1brfont size=-2Gawker/font/a/font/tdtd valign=top class=jfont style=font-size:85%;font-family:arial,sans-serifbrdiv style=padding-top:0.8em;img alt= height=1 width=1/divdiv class=lha href=http://news.google.com/news/url?sa=Tct=us/8-0fd=Rurl=http://gawker.com/5062332/geniuses-mike-huckabee-and-chuck-norris-compare-depression-conspiraciescid=1256896686ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNFFSrld8gfrlM0IDsN72e21HZ5xLgGeniuses Mike Huckabee and Chuck Norris Compare bDepression/b b.../b/abrfont size=-1font color=#6f6f6fGawker,nbsp;NYnbsp;-/font nobr9 hours ago/nobr/fontbrfont size=-1Don#39;t be a sucker. Those complicated, long-winded explanations of the worldwide financial crisis are just a lot of big city hokum. b.../b/font/div/font/td/tr/table

Stock Market Game Week in Review - TheStreet.com

table border=0 width= valign=top cellpadding=2 cellspacing=7trtd width=80 align=center valign=topfont style=font-size:85%;font-family:arial,sans-serifa href=http://news.google.com/news/url?sa=Tct=us/9i-0fd=Rurl=http://www.telegraph.co.uk/finance/personalfinance/3159517/A-bull-market-is-just-around-the-corner.htmlcid=1256654794ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNFk2Y1LmrWuZJSgx1QdH3rSDkMhSwimg src=http://news.google.com/news?imgefp=Kg6aK8ALcowJimgurl=www.telegraph.co.uk/telegraph/multimedia/archive/01006/YM-Bull_1006109c.jpg width=80 height=50 alt= border=1brfont size=-2Telegraph.co.uk/font/a/font/tdtd valign=top class=jfont style=font-size:85%;font-family:arial,sans-serifbrdiv style=padding-top:0.8em;img alt= height=1 width=1/divdiv class=lha href=http://news.google.com/news/url?sa=Tct=us/9-0fd=Rurl=http://www.thestreet.com/story/10441961/1/stock-market-game-week-in-review.html%3Fpuc%3Dgooglen%26cm_ven%3DGOOGLEN%26cm_cat%3DFREE%26cm_ite%3DNAcid=1256654794ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNGFajzheAWs0CyEcBCuO9iC9p-e3gStock Market Game Week in Review/abrfont size=-1font color=#6f6f6fTheStreet.comnbsp;-/font nobr4 hours ago/nobr/fontbrfont size=-1This is what happened in the Great bDepression/b. If you#39;re a business (or the government of California), you may have $1 million in accounts receivable b.../b/fontbrfont size=-1a href=http://news.google.com/news/url?sa=Tct=us/9-1fd=Rurl=http://seattletimes.nwsource.com/html/businesstechnology/2008256748_marksjarvis12.htmlcid=1256654794ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNFmLGan83IOhWwwOchfY2oHClZXbwHistory shows investors in stocks can bounce back in worst of times/a font size=-1 color=#6f6f6fnobrSeattle Times/nobr/font/fontbrfont size=-1a href=http://news.google.com/news/url?sa=Tct=us/9-2fd=Rurl=http://www.newsday.com/sports/olympics/sns-yourmoney-1012markets,0,4122322.storycid=1256654794ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNHz8BvCiPYwoA6wNZJ2vTdpRI8eewCertain financial truths remain in uncertain times/a font size=-1 color=#6f6f6fnobrNewsday/nobr/font/fontbrfont size=-1a href=http://news.google.com/news/url?sa=Tct=us/9-3fd=Rurl=http://www.washingtonpost.com/wp-dyn/content/article/2008/10/11/AR2008101100175.htmlcid=1256654794ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNENIFC3TApnUPXUYI0qiC8tXg9wcgStrap In for an Extended, Slow Recovery/a font size=-1 color=#6f6f6fnobrWashington Post/nobr/font/fontbrfont size=-1 class=pa href=http://news.google.com/news/url?sa=Tct=us/9-4fd=Rurl=http://www.philly.com/inquirer/business/20081012_Questions_to_help_you_decide_on_the_market.htmlcid=1256654794ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNGPWBf_AvgmfLYPEVjlCQKfWonK9QnobrPhiladelphia Inquirer/nobr/anbsp;- a href=http://news.google.com/news/url?sa=Tct=us/9-5fd=Rurl=http://www.telegraph.co.uk/finance/personalfinance/3159517/A-bull-market-is-around-the-corner.htmlcid=1256654794ei=-aTySOH0B5PK8ATpzYTABwusg=AFQjCNH0MqTTa2xe_9Myt0D1_XWWpmcDUQnobrTelegraph.co.uk/nobr/a/fontbr/font class=p size=-1a class=p href=http://news.google.com/news?sourceid=navclientie=ISO-8859-1rls=GGLG,GGLG:2005-22,GGLG:enncl=1256654794hl=ennobrall 22 news articles/nobr/a/font/div/font/td/tr/table

Depression - Google News

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Antidepressants: Control or Cure?
What's curious is that most of them will be on these drugs for life. Equally curious is that over seventy percent of people who stop taking them, for any length of time, will relapse into another painful episode of their illness.

How to Overcome Anxiety and Take Repossession of Your Life!
Katie came as close as is possible to having it all. Great job, loving family, boyfriend, social life? That was until she developed anxiety?"There were rumours of redundancy in our department.

Chronic Depression: Disease or Charcter Flaw?
A major survey on depression symptoms from the National Mental Health Association (NMHA), released in july 2001, revealed adramatic degree of progress in public understanding. Yet even amid this promising trend, the survey sheds light on thedifficulties faced by millions of people striving to manage this sometimes chronic, life-long illness.

Anxiety and Depression Treatment - 5 Tips for Beating Depression
Everyone has days when they are down, worn out and just notfeeling all that happy.That's OK, you need to have days like this, otherwise how wouldyou know when you are happy.

5 Tips to Reduce Depression
While war and poor economic conditions begin to affect people all over the world, more and more people suffer with depression. The more we focus on news events and the business climate, the more we are depressed.

Neuromodulation Is Now The Mainstream Therapy For Chronic Depression
The cover of the March 7, 2005 issue of Business Week titled REWIRING THE HUMAN BODY, describes how neuromodulation brings new hope to the four million desperate patients in the United States who suffer from the debilitating disease of chronic or treatment-resistant depression.The neuromodulation industry is just in its infancy and could double over the next several years as doctors are thrilled by this vision of the body electric.

Do Natural Stress, Anxiety, and Depression Supplements Really Work?
Unfortunately, millions of Americans currently suffer from the debilitating effects of stress, anxiety, and depression. In the pharmaceutical industry, anti-anxiety medications and antidepressants are among the best-selling medications on the market.